proSET Evo Fermentation System
£
proSET Evo Fermentation System
Description
proSET Evo System is the newest fermentor that offers an all-in-one fermentation solution and ultimate automation experience to ensure easy, smooth and productive bio-processing. The controller is pre-configured to support both thermostat and dry heating; together with its full compatibility to vessels from 0.5 to 20L, it provides a broad coverage to cultivation of most cell lines.
proSET Evo System is equipped with the latest control software; this user-friendly, intuitive software incorporates with many advanced functions to boost your experiment efficiency and thus lead to the success. Besides the manual controls of agitation, temperature, pH, DO level and feeding, one can also execute 15-step scheduled sequence controls on above parameters as well as pH and DO feedback controls. Moreover, a broad selection of plug-and-play optional devices are available to meet your specific requirement.
PC software connects up to 16 systems & 16 vessels at the same time.
This unit has a 12 month limited warranty, for more information, consult our terms and conditions.
| Control unit | Control panel | 10.4” color touch-screen Interface (Resolution: 800 x 600 pixels) |
| Communication port | Remote control through Ethernet | |
| Data export through USB port | ||
| Analog AUX port for system extension | ||
| Number of vessels controlled per remote control software | Max. 16 | |
| Program storage | Up to 59,994 programs for different kinds of condition | |
| Log data storage | Up to 100 process monitoring data files | |
| Cabinet material | ABS front panel and painted iron housing | |
| Dimension | Footprint: W x D = 15.75" x 22.44" (400mm x 570mm); Height: 29.14" (740mm) | |
| Rated voltage | 110V~/220V~; 50/60 Hz, 10A | |
| Aeration | Inlet gas flow-meter | 0, 0.1-1LPM (0.5L); 0, 0.4 - 5LPM (1L); 0, 1 - 10LPM (3, 5L); 0, 2 - 20LPM (10L); 0, 4 – 50LPM (15, 20L) |
| Sparger | Orifice ring | |
| Baffle | Removable 316L stainless steel baffles | |
| Temperature | Heating | 1. Thermostat System: built-in heat exchanger (550W heater, water circulation pump) |
| 2. Dry heating system (heating blanket or heating base unit) | ||
| Cooling | Cooling coil valve | |
| Range | with FS-V-A / B / C series : 5°C (41°F) above coolant up to 60°C (140°F); with FS-V-D series :5°C(41°F) above coolant up to 90°C (194°F); | |
| Probe | Platinum RTD probe (PT-100), non autoclavable | |
| Control mode | Manual or Programmable 15 steps PID control | |
| Agitation | Drive | Removable top brushless motor (M3 for 0.5L, 1L; M2 for 3~20L) |
| Speed range | a. For extremely shear-sensitive cell line: 30-300rpm b. For fermentation and cell culture: 30 - 1200rpm (0.5-5L); 30 - 1000rpm (10L); 30 – 700rpm(15, 20L) | |
| Resolution | 1rpm | |
| Impeller | 2 impellers for 0.5L &1L vessel and double jacketed vessels 3 impellers for 3L vessel and above Note: Customized impellers are available upon ordering | |
| Control mode | Manual or Programmable 15 steps PID control | |
| pH | Range | 2 - 14pH |
| Resolution | 0.01pH | |
| Probe | Gel-filled electrode, autoclavable | |
| Control mode | Manual/programmable 15 steps PID control with adjustable deadband, pH stat with smart feeding technology | |
| DO | Range | 0 - 200% |
| Resolution | 0.10% | |
| Probe | Polarographic DO sensor; autoclavable | |
| Control mode | 2-stage DO cascade response a. Increase or decrease agitation speed b. Oxygen Enrichment module(Optional) c. Gas Mixing Station module(Optional) DO stat with smart feeding technology | |
| ORP(optional) | Measurement range | -/ 2000mV |
| Resolution | 1mV | |
| Probe | Gel-filled electrode: autoclavable | |
| Foam / Level | Probe | 316L stainless steel protector with insulated PTFE tube, autoclavable, adjustable sensitivity control |
| Control Mode | Foam: On/Off switch Level: On/Off switch control with wet/dry probe set up | |
| Peristaltic Pump | Pump number | 4 x built-in pumps, 1 to 2 external pumps (Optional) |
| Motor type | Precise stepping motor; minimum speed is 1rpm | |
| Speed range | 0 to 65rpm | |
| Resolution | 1rpm | |
| Control mode | Manual or Programmable 15 steps feeding control; pump can be assigned for Acid, Base, Antifoam and/or Substrate; pump can calculate flow rate and total volume | |
| Exhaust | Device type | 316L stainless steel condenser |
System Specification
| Controller | Duo heating system controller | ||||
| Built-in rotameter | |||||
| 4 x built-in pump heads | |||||
| Vessel | Double jacketed vessel (includes glass body, head plate, T-handling bar, 2 probe adaptors) | Single wall dish bottom vessel (includes glass body, head plate, T-handling bar, 2 probe adaptors) | Airlifter vessel (includes glass body, head plate, draft tube, T-handling bar, 2 probe adaptors) | Single wall dish bottom with heating blanket (includes glass body, head plate, T-handling bar, 2 probe adaptors and heating blanket) | Single wall plain bottom with heating base unit (includes glass body, head plate, T-handling bar, 2 probe adaptors and heating base unit) |
| 2 adjustable Pitched-blade impeller | 3 adjustable Rushton-type impellers | no impellers | 3 adjustable Rushton-type impellers | 3 adjustable Rushton-type impellers | |
| Baffle assembled | Draft tube assembled | Baffle assembled | |||
| Condenser assembled | |||||
| Air sparger assembled | Micro sparger assembled | Air sparger assembled | |||
| Motor | Agitation motor | N / A | Agitation motor | ||
| Probes | 1x pH probe and 1x pH cable | ||||
| 1x Do probe and 1x DO cable | |||||
| 1x Temperature probe and 1x Temperature cable | |||||
| 1x anti-foam/level sensor and 1x anti-foam/level sensor cable | |||||
| Start-up Kit | Complete start-up kit includes, silicone tubes, tube clamps, metal connector and autoclavable disc filters | ||||
Vessel Specification
| Vessel | Double Jacketed (FS-V-A series) | Single Wall (FS-V-B series) | Air Lifter (FS-V-C series) | |||||||
| Working volume | 500ml | 1L | 3 L | 5 L | 10 L | 1L | 3 L | 5 L | 10 L | 5 L |
| Total volume | 1L | 1.5L | 3.8 L | 6.8 L | 12.5 L | 1.5 L | 3.8 L | 6.8 L | 12.5 L | 7 L |
| Vessel | Single Wall with Heating Blanket (FS-V-B series) | Single Wall with Heating Base Unit (FS-V-D series) | |||||||
| Working volume | 1L | 3 L | 5 L | 10 L | 15L | 20L | 3 L | 5 L | 10 L |
| Total volume | 1.5L | 3.8 L | 6.8 L | 12.5 L | 18L | 24.4L | 3.7 L | 6.4 L | 13.4L |
Utility Requirement
| Power source | 100-120V / 210-230V, 50-60Hz with electrical safety cutoff switch |
| Water source | 10 psig (0.69 barg), 14.5 psig (1 barg) maximum; (water supplied to fermenter must be softed and at least 15°C below set operating temperature) |
| Air source | 10 psig (0.69 barg), 29.0 psig (2 barg) maximum; air must be dry, oil-free and filtered |
| Sterilization | Autoclave; size of the autoclave inner chamber must be able to accomodate vessel with condenser attached |
This product has been cited in the following research papers:
| Reference title | Date | Citation | Product usage |
|---|---|---|---|
| Biosynthesis of chitosan-Oligosaccharides (COS) by non-aflatoxigenic Aspergillus sp. strain EGY1 DSM 101520: A robust biotechnological approach | 2018 | Amira M. Embaby, Ramy R. Melika, Ahmed Hussein, Amal H. El-Kamel, Heba S.Marey, Process Biochemistry, Volume 64, January 2018, Pages 16-30, | …Fig. 4. Batch cultivation of Aspergillus sp. section Flavi strain EGY1 DSM 101520 in a laboratory scale fermenter. Production medium (4 liters) with an initial pH of 5.0 in a 7-liters Cleaver laboratory scale fermenter was inoculated with 5% (v/v) seed culture previously grown for 72 h at 30 °C. The process was conducted at 25 °C under automated controlled pH. Each data point is expressed as the a… |
| Scaling-Up of Natural Products Isolation | 2012 | Cite this protocol as: Kumarasamy Y. (2012) Scaling-Up of Natural Products Isolation. In: Sarker S., Nahar L. (eds) Natural Products Isolation. Methods in Molecular Biology (Methods and Protocols), vol 864. Humana Press | … useful feature of this system is that it is available with interchangeable vessels which range from 2.2 L to 14.0 L. Other companies that produce similar fermentors include Minifors®, Lavalabs®, and Cleaver Scientific. Bench-top fermenters are usually cheaper to purchase than the trolley mounted or skid-mounted fermenters. The entry level fermentors are simple in construction and can be thought o… |
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